The A406 is closed off between Harrow Road and Hanger Lane
Three people have been injured after a lorry and two cars were involved in a smash on the North Circular Road in Park Royal.
The heavy goods vehicle hit the central reservation and overturned on the A406 near Brentmead Gardens at around 12.30pm.
Two cars were also involved in the crash.
The three injured people were treated at the scene.
Drivers are being warned to avoid the area as the A406 has been closed off between Harrow Road and Hanger Lane.
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